Inducible SMARCAL1 knockdown in iPSC reveals a link between replication stress and altered expression of master differentiation genes

Schimke immuno-osseous dysplasia is an autosomal recessive genetic osteochondrodysplasia characterized by dysmorphism, spondyloepiphyseal dysplasia, nephrotic syndrome and frequently T cell immunodeficiency. Several hypotheses have been proposed to explain the pathophysiology of the disease; however...

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Detalles Bibliográficos
Autores principales: Pugliese, Giusj Monia, Salaris, Federico, Palermo, Valentina, Marabitti, Veronica, Morina, Nicolò, Rosa, Alessandro, Franchitto, Annapaola, Pichierri, Pietro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826020/
https://www.ncbi.nlm.nih.gov/pubmed/31515241
http://dx.doi.org/10.1242/dmm.039487

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826020/
https://www.ncbi.nlm.nih.gov/pubmed/31515241
http://dx.doi.org/10.1242/dmm.039487

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