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Reversion of tumor hepatocytes to normal hepatocytes during liver tumor regression in an oncogene-expressing transgenic zebrafish model

Tumors are frequently dependent on primary oncogenes to maintain their malignant properties (known as ‘oncogene addiction’). We have previously established several inducible hepatocellular carcinoma (HCC) models in zebrafish by transgenic expression of an oncogene. These tumor models are strongly on...

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Detalles Bibliográficos
Autores principales: Li, Yan, Agrawal, Ira, Gong, Zhiyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826027/
https://www.ncbi.nlm.nih.gov/pubmed/31515263
http://dx.doi.org/10.1242/dmm.039578