Cargando…

Inflammasome-Independent Role for NLRP3 in Controlling Innate Antihelminth Immunity and Tissue Repair in the Lung

Alternatively activated macrophages are essential effector cells during type 2 immunity and tissue repair following helminth infections. We previously showed that Ym1, an alternative activation marker, can drive innate IL-1R–dependent neutrophil recruitment during infection with the lung-migrating n...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chenery, Alistair L., Alhallaf, Rafid, Agha, Zainab, Ajendra, Jesuthas, Parkinson, James E., Cooper, Martha M., Chan, Brian H. K., Eichenberger, Ramon M., Dent, Lindsay A., Robertson, Avril A. B., Kupz, Andreas, Brough, David, Loukas, Alex, Sutherland, Tara E., Allen, Judith E., Giacomin, Paul R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AAI 2019
Materias:	Mucosal Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826118/ https://www.ncbi.nlm.nih.gov/pubmed/31586037 http://dx.doi.org/10.4049/jimmunol.1900640

Ejemplares similares

Gastrointestinal Helminth Infection Improves Insulin Sensitivity, Decreases Systemic Inflammation, and Alters the Composition of Gut Microbiota in Distinct Mouse Models of Type 2 Diabetes
por: Khudhair, Zainab, et al.
Publicado: (2021)

Mitogenetic effect of saliva to peripheral lymphocytes in patients with oral cancer and chronic nasopharyngeal infections
por: Kologrivova, E.N., et al.
Publicado: (1997)

NAD metabolism fuels human and mouse intestinal inflammation
por: Gerner, Romana R, et al.
Publicado: (2018)

IL-33 Augments Virus-Specific Memory T Cell Inflation and Potentiates the Efficacy of an Attenuated Cytomegalovirus-Based Vaccine
por: McLaren, James E., et al.
Publicado: (2019)

MicroRNA-142 Critically Regulates Group 2 Innate Lymphoid Cell Homeostasis and Function
por: Roberts, Luke B., et al.
Publicado: (2021)

Human duodenum responses to vitamin D metabolites of TRPV6 and other genes involved in calcium absorption
por: Balesaria, Sara, et al.
Publicado: (2009)

The apical (hPepT1) and basolateral peptide transport systems of Caco-2 cells are regulated by AMP-activated protein kinase
por: Pieri, Myrtani, et al.
Publicado: (2010)

Luminal Microbes Promote Monocyte–Stem Cell Interactions Across a Healthy Colonic Epithelium
por: Skoczek, Dagmara A., et al.
Publicado: (2014)

Dynamic Changes in Macrophage Activation and Proliferation during the Development and Resolution of Intestinal Inflammation
por: Little, Matthew C., et al.
Publicado: (2014)

The role of plasminogen activator inhibitor-1 in gastric mucosal protection
por: Kenny, Susan, et al.
Publicado: (2013)

Prolactin mediates psychological stress-induced dysfunction of regulatory T cells to facilitate intestinal inflammation
por: Wu, Wei, et al.
Publicado: (2014)

Distinct afferent innervation patterns within the human proximal and distal esophageal mucosa
por: Woodland, Philip, et al.
Publicado: (2015)

Bimodal Expansion of the Lymphatic Vessels Is Regulated by the Sequential Expression of IL-7 and Lymphotoxin α(1)β(2) in Newly Formed Tertiary Lymphoid Structures
por: Nayar, Saba, et al.
Publicado: (2016)

Salmonella enterica Serovar Typhimurium Travels to Mesenteric Lymph Nodes Both with Host Cells and Autonomously
por: Bravo-Blas, Alberto, et al.
Publicado: (2019)

The Roles of Type 2 Cytotoxic T Cells in Inflammation, Tissue Remodeling, and Prostaglandin (PG) D(2) Production Are Attenuated by PGD(2) Receptor 2 Antagonism
por: Chen, Wentao, et al.
Publicado: (2021)

Cytokine gene expression in mucosal T lymphocyte populations
por: O'Keeffe, J., et al.
Publicado: (1997)

Simultaneous Aerosol and Intramuscular Immunization with Influenza Vaccine Induces Powerful Protective Local T Cell and Systemic Antibody Immune Responses in Pigs
por: Martini, Veronica, et al.
Publicado: (2021)

IL-17A both initiates, via IFNγ suppression, and limits the pulmonary type-2 immune response to nematode infection
por: Ajendra, Jesuthas, et al.
Publicado: (2020)

Administration of Hookworm Excretory/Secretory Proteins Improves Glucose Tolerance in a Mouse Model of Type 2 Diabetes
por: Khudhair, Zainab, et al.
Publicado: (2022)

Extent of Ischemic Brain Injury After Thrombotic Stroke Is Independent of the NLRP3 (NACHT, LRR and PYD Domains-Containing Protein 3) Inflammasome
por: Lemarchand, Eloise, et al.
Publicado: (2019)

IL-13 deficiency exacerbates lung damage and impairs epithelial-derived type 2 molecules during nematode infection
por: Chenery, Alistair L, et al.
Publicado: (2021)

Inhibiting the NLRP3 Inflammasome
por: El-Sharkawy, Lina Y., et al.
Publicado: (2020)

Niclosamide: Beyond an antihelminthic drug
por: Chen, Wei, et al.
Publicado: (2018)

Antihelminthic niclosamide modulates dendritic cells activation and function
por: Wu, Chieh-Shan, et al.
Publicado: (2014)

The NLRP3–inflammasome as a sensor of organelle dysfunction
por: Seoane, Paula I., et al.
Publicado: (2020)

Design, Synthesis and Evaluation of Oxazaborine Inhibitors of the NLRP3 Inflammasome
por: Baldwin, Alex G., et al.
Publicado: (2018)

Inhibition of the NLRP3 inflammasome by HSP90 inhibitors
por: Nizami, Sohaib, et al.
Publicado: (2020)

Preclinical evaluation of a nanoformulated antihelminthic, niclosamide, in ovarian cancer
por: Lin, Chi-Kang, et al.
Publicado: (2016)

Antihelminthics in helminth‐endemic areas: effects on HIV disease progression
por: Means, Arianna Rubin, et al.
Publicado: (2016)

Development of patent Litomosoides sigmodontis infections in semi-susceptible C57BL/6 mice in the absence of adaptive immune responses
por: Layland, Laura E., et al.
Publicado: (2015)

Sphingosine regulates the NLRP3-inflammasome and IL-1β release from macrophages
por: Luheshi, Nadia M, et al.
Publicado: (2012)

Itaconate and fumarate derivatives inhibit priming and activation of the canonical NLRP3 inflammasome in macrophages
por: Hoyle, Christopher, et al.
Publicado: (2022)

Boron-Based Inhibitors of the NLRP3 Inflammasome
por: Baldwin, Alex G., et al.
Publicado: (2017)

Hallmarks of NLRP3 inflammasome activation are observed in organotypic hippocampal slice culture
por: Hoyle, Christopher, et al.
Publicado: (2020)

Priming Is Dispensable for NLRP3 Inflammasome Activation in Human Monocytes In Vitro
por: Gritsenko, Anna, et al.
Publicado: (2020)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

USP7 and USP47 deubiquitinases regulate NLRP3 inflammasome activation
por: Palazón‐Riquelme, Pablo, et al.
Publicado: (2018)

Immunological Consequences of Antihelminthic Treatment in Preschool Children Exposed to Urogenital Schistosome Infection
por: Rujeni, Nadine, et al.
Publicado: (2013)

Recent large-scale philophthalmosis outbreak in Portugal: inefficacy of common antihelminthic agents
por: Heneberg, Petr, et al.
Publicado: (2022)

The antihelminth drug rafoxanide reverses chromosomal-mediated colistin-resistance in Klebsiella pneumoniae
por: Han, Rongjia, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_82re6nuhkcb5ead2qd02hmo6gu