Long‐term repopulation of aged bone marrow stem cells using young Sca‐1 cells promotes aged heart rejuvenation

Reduced quantity and quality of stem cells in aged individuals hinders cardiac repair and regeneration after injury. We used young bone marrow (BM) stem cell antigen 1 (Sca‐1) cells to reconstitute aged BM and rejuvenate the aged heart, and examined the underlying molecular mechanisms. BM Sca‐1(+) o...

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Detalles Bibliográficos
Autores principales: Li, Jiao, Li, Shu‐Hong, Dong, Jun, Alibhai, Faisal J., Zhang, Chongyu, Shao, Zheng‐Bo, Song, Hui‐Fang, He, Sheng, Yin, Wen‐Juan, Wu, Jun, Weisel, Richard D., Liu, Shi‐Ming, Li, Ren‐Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826122/
https://www.ncbi.nlm.nih.gov/pubmed/31385396
http://dx.doi.org/10.1111/acel.13026

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