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Loss of HDAC3 contributes to meiotic defects in aged oocytes

Maternal age‐related decline in oocyte quality is associated with meiotic defects, but the underlying mechanisms remain to be explored. Histone deacetylase 3 (HDAC3) has been shown to govern multiple cellular events via deacetylating diverse substrates. We previously found that HDAC3 could promote m...

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Detalles Bibliográficos
Autores principales: He, Yongfu, Li, Xiaoyan, Gao, Min, Liu, Honglin, Gu, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826132/
https://www.ncbi.nlm.nih.gov/pubmed/31498540
http://dx.doi.org/10.1111/acel.13036