SLC1A3 contributes to L‐asparaginase resistance in solid tumors

L‐asparaginase (ASNase) serves as an effective drug for adolescent acute lymphoblastic leukemia. However, many clinical trials indicated severe ASNase toxicity in patients with solid tumors, with resistant mechanisms not well understood. Here, we took a functional genetic approach and identified SLC...

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Detalles Bibliográficos
Autores principales: Sun, Jianhui, Nagel, Remco, Zaal, Esther A, Ugalde, Alejandro Piñeiro, Han, Ruiqi, Proost, Natalie, Song, Ji‐Ying, Pataskar, Abhijeet, Burylo, Artur, Fu, Haigen, Poelarends, Gerrit J, van de Ven, Marieke, van Tellingen, Olaf, Berkers, Celia R, Agami, Reuven
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826201/
https://www.ncbi.nlm.nih.gov/pubmed/31523835
http://dx.doi.org/10.15252/embj.2019102147

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826201/
https://www.ncbi.nlm.nih.gov/pubmed/31523835
http://dx.doi.org/10.15252/embj.2019102147

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