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Luminal-contact-inhibition of epithelial basal stem cell multipotency in prostate organogenesis and homeostasis

Prostate epithelial basal cells are highly plastic in their luminal differentiation capability. Basal stem cells actively produce luminal cells during organogenesis, but become restricted in the adult prostate unless receiving oncogenic or inflammatory stimuli. Given that the number of luminal cells...

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Detalles Bibliográficos
Autores principales: Horton, Corrigan, Liu, Yueli, Yu, Chuan, Xie, Qing, Wang, Zhu A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826291/
https://www.ncbi.nlm.nih.gov/pubmed/31540905
http://dx.doi.org/10.1242/bio.045724

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