Acid sphingomyelinase regulates the localization and trafficking of palmitoylated proteins

In human, loss of acid sphingomyelinase (ASM/SMPD1) causes Niemann–Pick disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. Our mass spectrometry-based proteomic analyses have identified >100 proteins associated with the ASM-depen...

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Detalles Bibliográficos
Autores principales: Xiong, Xiahui, Lee, Chia-Fang, Li, Wenjing, Yu, Jiekai, Zhu, Linyu, Kim, Yongsoon, Zhang, Hui, Sun, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826292/
https://www.ncbi.nlm.nih.gov/pubmed/31142470
http://dx.doi.org/10.1242/bio.040311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826292/
https://www.ncbi.nlm.nih.gov/pubmed/31142470
http://dx.doi.org/10.1242/bio.040311

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