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Acid sphingomyelinase regulates the localization and trafficking of palmitoylated proteins

In human, loss of acid sphingomyelinase (ASM/SMPD1) causes Niemann–Pick disease, type A. ASM hydrolyzes sphingomyelins to produce ceramides but protein targets of ASM remain largely unclear. Our mass spectrometry-based proteomic analyses have identified >100 proteins associated with the ASM-depen...

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Detalles Bibliográficos
Autores principales:	Xiong, Xiahui, Lee, Chia-Fang, Li, Wenjing, Yu, Jiekai, Zhu, Linyu, Kim, Yongsoon, Zhang, Hui, Sun, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Company of Biologists Ltd 2019
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826292/ https://www.ncbi.nlm.nih.gov/pubmed/31142470 http://dx.doi.org/10.1242/bio.040311

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