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Targeting of copper-trafficking chaperones causes gene-specific systemic pathology in Drosophila melanogaster: prospective expansion of mutational landscapes that regulate tumor resistance to cisplatin
Copper, a transition metal, is an essential component for normal growth and development. It acts as a critical co-factor of many enzymes that play key roles in diverse cellular processes. The present study attempts to investigate the regulatory functions decisively controlling copper trafficking dur...
Autores principales: | Theotoki, Eleni I., Velentzas, Athanassios D., Katarachia, Stamatia A., Papandreou, Nikos C., Kalavros, Nikolas I., Pasadaki, Sofia N., Giannopoulou, Aikaterini F., Giannios, Panagiotis, Iconomidou, Vassiliki A., Konstantakou, Eumorphia G., Anastasiadou, Ema, Papassideri, Issidora S., Stravopodis, Dimitrios J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists Ltd
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826294/ https://www.ncbi.nlm.nih.gov/pubmed/31575544 http://dx.doi.org/10.1242/bio.046961 |
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