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Thioredoxin Downregulation Enhances Sorafenib Effects in Hepatocarcinoma Cells

Sorafenib is the first-line recommended therapy for patients with advanced hepatocarcinoma (HCC) in de-differentiation stage (presenting epithelial–mesenchymal transition, EMT). We studied the role of the thioredoxin system (Trx1/TrxR1) in the sensitivity or resistance of HCC cells to the treatment...

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Detalles Bibliográficos
Autores principales:	López-Grueso, María José, González, Raúl, Muntané, Jordi, Bárcena, José Antonio, Padilla, C. Alicia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826379/ https://www.ncbi.nlm.nih.gov/pubmed/31652503 http://dx.doi.org/10.3390/antiox8100501

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