Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols

Polyphenols are probably the most important family of natural and synthetic chain-breaking antioxidants. Since long ago, chemists have studied how structural (bioinspired) modifications can improve the antioxidant activity of these compounds in terms of reaction rate with radical reactive oxygen spe...

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Detalles Bibliográficos
Autores principales: Viglianisi, Caterina, Menichetti, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826409/
https://www.ncbi.nlm.nih.gov/pubmed/31623080
http://dx.doi.org/10.3390/antiox8100487
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author Viglianisi, Caterina
Menichetti, Stefano
author_facet Viglianisi, Caterina
Menichetti, Stefano
author_sort Viglianisi, Caterina
collection PubMed
description Polyphenols are probably the most important family of natural and synthetic chain-breaking antioxidants. Since long ago, chemists have studied how structural (bioinspired) modifications can improve the antioxidant activity of these compounds in terms of reaction rate with radical reactive oxygen species (ROS), catalytic character, multi-defence action, hydrophilicity/lipophilicity, biodistribution etc. In this framework, we will discuss the effect played on the overall antioxidant profile by the insertion of heavy chalcogens (S, Se and Te) in the phenolic skeleton.
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spelling pubmed-68264092019-11-18 Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols Viglianisi, Caterina Menichetti, Stefano Antioxidants (Basel) Review Polyphenols are probably the most important family of natural and synthetic chain-breaking antioxidants. Since long ago, chemists have studied how structural (bioinspired) modifications can improve the antioxidant activity of these compounds in terms of reaction rate with radical reactive oxygen species (ROS), catalytic character, multi-defence action, hydrophilicity/lipophilicity, biodistribution etc. In this framework, we will discuss the effect played on the overall antioxidant profile by the insertion of heavy chalcogens (S, Se and Te) in the phenolic skeleton. MDPI 2019-10-16 /pmc/articles/PMC6826409/ /pubmed/31623080 http://dx.doi.org/10.3390/antiox8100487 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Review
Viglianisi, Caterina
Menichetti, Stefano
Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols
title Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols
title_full Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols
title_fullStr Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols
title_full_unstemmed Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols
title_short Chain Breaking Antioxidant Activity of Heavy (S, Se, Te) Chalcogens Substituted Polyphenols
title_sort chain breaking antioxidant activity of heavy (s, se, te) chalcogens substituted polyphenols
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826409/
https://www.ncbi.nlm.nih.gov/pubmed/31623080
http://dx.doi.org/10.3390/antiox8100487
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