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Validation of Hepatocellular Carcinoma Experimental Models for TGF-β Promoting Tumor Progression

Transforming growth factor beta (TGF-β) is a pleiotropic cytokine with dual role in hepatocellular carcinoma (HCC). It acts as tumor-suppressor and tumor-promoter in the early and late stage respectively. TGF-β influences the tumor-stroma cross-talk affecting the tumoral microenvironment. Therefore,...

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Detalles Bibliográficos
Autores principales: Mancarella, Serena, Krol, Silke, Crovace, Alberto, Leporatti, Stefano, Dituri, Francesco, Frusciante, Martina, Giannelli, Gianluigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826694/
https://www.ncbi.nlm.nih.gov/pubmed/31600917
http://dx.doi.org/10.3390/cancers11101510