Nitroethanol in Comparison with Monensin Exhibits Greater Feed Efficiency Through Inhibiting Rumen Methanogenesis More Efficiently and Persistently in Feedlotting Lambs

SIMPLE SUMMARY: This study aimed to determine dietary supplemental effects of nitroethanol (NEOH) in comparison with monensin on growth performance, nutrient digestibility, rumen fermentation characteristics and methane production in feedlotting lambs. The dietary addition of NEOH in comparison with monensin presented a greater promoting effect on growth performance in feedlotting lambs by inhibiting methanogenesis more efficiently and persistently in the rumen. Although dietary NEOH or monensin addition did not affect nutrient digestibility in the whole digestion tract, they presented a distinct action mode of regulating ruminal volatile fatty acids (VFAs) and methane production. ABSTRACT: This study was conducted to determine the dietary supplemental effects of nitroethanol (NEOH) in comparison with monensin on growth performance and estimated methane (CH(4)) production in feedlotting lambs. Sixty male, small-tailed Chinese Han lambs were arranged at random into three dietary treatment groups: (1) a basal control diet (CTR), (2) the basal diet added with 40 mg/kg monensin (MON), (3) the basal diet added with 277 mg/kg nitroethanol (NEOH). During the 32-day lamb feeding, monensin and nitroethanol were added in period 1 (day 0–16) and then withdrawn in the subsequent period 2 (day 17–32) to determine their withdrawal effects. The average daily gain (ADG) and feed conversion rate in the whole period ranked: NEOH > MON > CTR (p < 0.01), suggesting that the dietary addition of NEOH in comparison with monensin presented a more lasting beneficial effect on feed efficiency. Methane emission was estimated with rumen VFA production and gross energy intake. Both monensin and NEOH addition in comparison with the control remarkably decreased CH(4) emission estimate (24.0% vs. 26.4% decrease; p < 0.01) as well as CH(4) emission per kg ADG (8.7% vs. 14.0% decrease; p < 0.01), but the NEOH group presented obvious lasting methanogenesis inhibition when they were withdrawn in period 2. Moreover, the in vitro methanogenic activity of rumen fluids was also decreased with monensin or NEOH addition (12.7% vs. 30.5% decrease; p < 0.01). In summary, the dietary addition of NEOH in comparison with monensin presented a greater promoting effect on growth performance in feedlotting lambs by inhibiting rumen methanogenesis more efficiently and persistently.