FOXO1 Confers Maintenance of the Dark Zone Proliferation and Survival Program and Can Be Pharmacologically Targeted in Burkitt Lymphoma

The FOXO1 transcription factor plays a central role in the proliferation and survival of B cells at several stages of differentiation. B cell malignancies, with exception of classical Hodgkin lymphoma, maintain expression of FOXO1 at levels characteristic for their non-malignant counterparts. Extens...

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Detalles Bibliográficos
Autores principales: Gehringer, Franziska, Weissinger, Stephanie E, Swier, Lotteke JYM, Möller, Peter, Wirth, Thomas, Ushmorov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826697/
https://www.ncbi.nlm.nih.gov/pubmed/31557894
http://dx.doi.org/10.3390/cancers11101427

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