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An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara)

The red-spotted grouper (Epinephelus akaara) is one of the most commercially important aquatic species in China. However, its seedstock has low larval survival rates, and its stability is confronted with the danger of overexploitation. In this study, a high-density genetic map was constructed using...

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Autores principales: Wang, Xiang, Jiang, Shoujia, Zheng, Leyun, Xiao, Ling, Zhang, Xinhui, Wang, Dengdong, Li, Shuisheng, Shi, Qiong, Wu, Shuiqing, Lin, Haoran, You, Xinxin, Zhang, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826704/
https://www.ncbi.nlm.nih.gov/pubmed/31614822
http://dx.doi.org/10.3390/genes10100793
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author Wang, Xiang
Jiang, Shoujia
Zheng, Leyun
Xiao, Ling
Zhang, Xinhui
Wang, Dengdong
Li, Shuisheng
Shi, Qiong
Wu, Shuiqing
Lin, Haoran
You, Xinxin
Zhang, Yong
author_facet Wang, Xiang
Jiang, Shoujia
Zheng, Leyun
Xiao, Ling
Zhang, Xinhui
Wang, Dengdong
Li, Shuisheng
Shi, Qiong
Wu, Shuiqing
Lin, Haoran
You, Xinxin
Zhang, Yong
author_sort Wang, Xiang
collection PubMed
description The red-spotted grouper (Epinephelus akaara) is one of the most commercially important aquatic species in China. However, its seedstock has low larval survival rates, and its stability is confronted with the danger of overexploitation. In this study, a high-density genetic map was constructed using 3435 single nucleotide polymorphisms (SNPs) from 142 first generation (F(1)) full-sib offspring and two parents of a red-spotted grouper population. The total genetic length of the map was 2300.12 cM with an average intermarker distance of 0.67 cM. Seventeen genome-wide significant quantitative trait loci (QTLs) for growth-related traits were detected on 24 linkage groups, including 5 QTLs for full length, 7 QTLs for body length, and 5 QTLs for body weight. The contribution values of explained phenotypic variance ranged from 10.7% to 12.9%. Moreover, 13 potential candidate genes for growth-related traits were identified. Collectively, these findings will be useful for conducting marker-assisted selection of the red-spotted grouper in future studies.
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spelling pubmed-68267042019-11-18 An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara) Wang, Xiang Jiang, Shoujia Zheng, Leyun Xiao, Ling Zhang, Xinhui Wang, Dengdong Li, Shuisheng Shi, Qiong Wu, Shuiqing Lin, Haoran You, Xinxin Zhang, Yong Genes (Basel) Article The red-spotted grouper (Epinephelus akaara) is one of the most commercially important aquatic species in China. However, its seedstock has low larval survival rates, and its stability is confronted with the danger of overexploitation. In this study, a high-density genetic map was constructed using 3435 single nucleotide polymorphisms (SNPs) from 142 first generation (F(1)) full-sib offspring and two parents of a red-spotted grouper population. The total genetic length of the map was 2300.12 cM with an average intermarker distance of 0.67 cM. Seventeen genome-wide significant quantitative trait loci (QTLs) for growth-related traits were detected on 24 linkage groups, including 5 QTLs for full length, 7 QTLs for body length, and 5 QTLs for body weight. The contribution values of explained phenotypic variance ranged from 10.7% to 12.9%. Moreover, 13 potential candidate genes for growth-related traits were identified. Collectively, these findings will be useful for conducting marker-assisted selection of the red-spotted grouper in future studies. MDPI 2019-10-12 /pmc/articles/PMC6826704/ /pubmed/31614822 http://dx.doi.org/10.3390/genes10100793 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Wang, Xiang
Jiang, Shoujia
Zheng, Leyun
Xiao, Ling
Zhang, Xinhui
Wang, Dengdong
Li, Shuisheng
Shi, Qiong
Wu, Shuiqing
Lin, Haoran
You, Xinxin
Zhang, Yong
An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara)
title An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara)
title_full An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara)
title_fullStr An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara)
title_full_unstemmed An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara)
title_short An SNP-Based Genetic Map and QTL Mapping for Growth Traits in the Red-Spotted Grouper (Epinephelus akaara)
title_sort snp-based genetic map and qtl mapping for growth traits in the red-spotted grouper (epinephelus akaara)
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826704/
https://www.ncbi.nlm.nih.gov/pubmed/31614822
http://dx.doi.org/10.3390/genes10100793
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