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Histone Deacetylase Expressions in Hepatocellular Carcinoma and Functional Effects of Histone Deacetylase Inhibitors on Liver Cancer Cells In Vitro

Hepatocellular carcinoma (HCC) is a leading cause for deaths worldwide. Histone deacetylase (HDAC) inhibition (HDACi) is emerging as a promising therapeutic strategy. However, most pharmacological HDACi unselectively block different HDAC classes and their molecular mechanisms of action are only inco...

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Detalles Bibliográficos
Autores principales: Freese, Kim, Seitz, Tatjana, Dietrich, Peter, Lee, Serene M.L., Thasler, Wolfgang E., Bosserhoff, Anja, Hellerbrand, Claus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826839/
https://www.ncbi.nlm.nih.gov/pubmed/31635225
http://dx.doi.org/10.3390/cancers11101587

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