Replication Stress Response Links RAD52 to Protecting Common Fragile Sites

Rad52 in yeast is a key player in homologous recombination (HR), but mammalian RAD52 is dispensable for HR as shown by the lack of a strong HR phenotype in RAD52-deficient cells and in RAD52 knockout mice. RAD52 function in mammalian cells first emerged with the discovery of its important backup rol...

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Detalles Bibliográficos
Autor principal: Wu, Xiaohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826974/
https://www.ncbi.nlm.nih.gov/pubmed/31569559
http://dx.doi.org/10.3390/cancers11101467

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6826974/
https://www.ncbi.nlm.nih.gov/pubmed/31569559
http://dx.doi.org/10.3390/cancers11101467

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