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Apalutamide Sensitizes Prostate Cancer to Ionizing Radiation via Inhibition of Non-Homologous End-Joining DNA Repair

Androgen-deprivation therapy was shown to improve treatment outcome of external beam radiation therapy (EBRT) for locally advanced prostate cancer (PCa). DNA damage response (DDR) was suggested to play a role in the underlying mechanism, but conflicting results were reported. This study aims to reve...

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Detalles Bibliográficos
Autores principales:	Zhang, Wenhao, Liao, Chen-Yi, Chtatou, Hajar, Incrocci, Luca, van Gent, Dik C., van Weerden, Wytske M., Nonnekens, Julie
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827010/ https://www.ncbi.nlm.nih.gov/pubmed/31635359 http://dx.doi.org/10.3390/cancers11101593

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