Cargando…

(99m)Tc-A1 as a Novel Imaging Agent Targeting Mesothelin-Expressing Pancreatic Ductal Adenocarcinoma

Mesothelin is a membrane-associated protein overexpressed in pancreatic ductal adenocarcinoma (PDAC). Some mesothelin-targeted therapies are in clinical development but the identification of patients eligible for such therapies is still challenging. The objective of this study was to perform the ima...

Descripción completa

Detalles Bibliográficos
Autores principales:	Montemagno, Christopher, Cassim, Shamir, Trichanh, Dimitry, Savary, Clara, Pouyssegur, Jacques, Pagès, Gilles, Fagret, Daniel, Broisat, Alexis, Ghezzi, Catherine
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Brief Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827014/ https://www.ncbi.nlm.nih.gov/pubmed/31658755 http://dx.doi.org/10.3390/cancers11101531

Ejemplares similares

From Malignant Progression to Therapeutic Targeting: Current Insights of Mesothelin in Pancreatic Ductal Adenocarcinoma
por: Montemagno, Christopher, et al.
Publicado: (2020)

Pancreatic Ductal Adenocarcinoma: The Dawn of the Era of Nuclear Medicine?
por: Montemagno, Christopher, et al.
Publicado: (2021)

Overexpression of Mesothelin in Pancreatic Ductal Adenocarcinoma (PDAC)
por: Le, Kai, et al.
Publicado: (2020)

Fibulin1 and mesothelin expressions in pancreas ductal adenocarcinoma
por: Aksoy, Asude, et al.
Publicado: (2023)

Tumor Microenvironment: A Metabolic Player that Shapes the Immune Response
por: Cassim, Shamir, et al.
Publicado: (2019)

Metabolic Rewiring toward Oxidative Phosphorylation Disrupts Intrinsic Resistance to Ferroptosis of the Colon Adenocarcinoma Cells
por: Gotorbe, Célia, et al.
Publicado: (2022)

Non-invasive Multimodality Imaging of Coronary Vulnerable Patient
por: Canu, Marjorie, et al.
Publicado: (2022)

Warburg and Beyond: The Power of Mitochondrial Metabolism to Collaborate or Replace Fermentative Glycolysis in Cancer
por: Cassim, Shamir, et al.
Publicado: (2020)

Histoepigenetic analysis of the mesothelin network within pancreatic ductal adenocarcinoma cells reveals regulation of retinoic acid receptor gamma and AKT by mesothelin
por: Lurie, Eugene, et al.
Publicado: (2020)

Together we stand, apart we fall: how cell-to-cell contact/interplay provides resistance to ferroptosis
por: Vucetic, Milica, et al.
Publicado: (2020)

Periaortic Brown Adipose Tissue as a Major Determinant of [(18)F]-Fluorodeoxyglucose Vascular Uptake in Atherosclerosis-Prone, ApoE(−/−) Mice
por: Toczek, Jakub, et al.
Publicado: (2014)

In Vivo Assessment of VCAM-1 Expression by SPECT/CT Imaging in Mice Models of Human Triple Negative Breast Cancer
por: Montemagno, Christopher, et al.
Publicado: (2019)

Comparison of [(99m)Tc]Tc-tilmanocept with [(99m)Tc]Tc-sulphur colloids and [(99m)Tc]Tc-albumin colloids for sentinel lymph node detection in patients with cutaneous malignancies of the head
por: Ooms, Mark, et al.
Publicado: (2022)

Clinical usefulness of (99m)Tc-HYNIC-TOC, (99m)Tc(V)-DMSA, and (99m)Tc-MIBI SPECT in the evaluation of pituitary adenomas
por: Vukomanovic, Vladimir R., et al.
Publicado: (2019)

Head to head comparison of [(99m)Tc]Tc(CO)(3)(NTA) and [(99m)Tc]Tc-MAG3 in patients with suspected obstruction
por: Taylor, Andrew T., et al.
Publicado: (2021)

Systematic evaluation of (99m)Tc-tetrofosmin versus (99m)Tc-sestamibi to study murine myocardial perfusion in small animal SPECT/CT
por: Vrachimis, Alexis, et al.
Publicado: (2012)

Pharmacokinetics of the phosphatidylserine tracers (99m)Tc-lactadherin and (99m)Tc-annexin V in pigs
por: Poulsen, Runa H, et al.
Publicado: (2013)

Altered [(99m)Tc]Tc-MDP biodistribution from neutron activation sourced (99)Mo
por: Demeter, Sandor, et al.
Publicado: (2018)

Sentinel lymph node detection in oral cancer: a within-patient comparison between [(99m)Tc]Tc-tilmanocept and [(99m)Tc]Tc-nanocolloid
por: den Toom, Inne J., et al.
Publicado: (2020)

Comparing (99m)Tc-PSMA to (99m)Tc-MDP in Prostate Cancer Staging of the Skeletal System
por: Kabunda, Joseph, et al.
Publicado: (2021)

Mesothelin Expression in Gastric Adenocarcinoma and Its Relation to Clinical Outcomes
por: Han, Song-Hee, et al.
Publicado: (2017)

(95g)Tc and (96g)Tc as alternatives to medical radioisotope (99m)Tc
por: Hayakawa, Takehito, et al.
Publicado: (2018)

(99m)Tc-besilesomab (Scintimun®) in peripheral osteomyelitis: comparison with (99m)Tc-labelled white blood cells
por: Richter, Wolf S., et al.
Publicado: (2011)

Study of Binding Kinetics and Specificity of (99m)Tc-SSS-Complex and (99m)Tc-HMPAO to Blood Cells
por: Auletta, S., et al.
Publicado: (2018)

(99m)Tc-Radiolabeled TPGS Nanomicelles Outperform (99m)Tc-Sestamibi as Breast Cancer Imaging Agent
por: Tesan, Fiorella C., et al.
Publicado: (2019)

Mapping of brain tissue hematocrit in glioma and acute stroke using a dual autoradiography approach
por: Broisat, A., et al.
Publicado: (2018)

Anaphylactic Reaction to Tc-99m Macrosalb
por: Schreuder, Nanno, et al.
Publicado: (2019)

Diagnostic accuracy of [(99m)Tc]Tc-Sestamibi in the assessment of thyroid nodules
por: Yordanova, Anna, et al.
Publicado: (2017)

Imaging Hydrogen Sulfide in Hypoxic Tissue with [(99m)Tc]Tc-Gluconate
por: Kweon, Yongkyoung, et al.
Publicado: (2020)

Magnesium-Molybate Compounds as Matrix for (99)Mo/(99m)Tc Generators
por: Monroy-Guzman, Fabiola, et al.
Publicado: (2011)

A Cystine-Cysteine Intercellular Shuttle Prevents Ferroptosis in xCT(KO) Pancreatic Ductal Adenocarcinoma Cells
por: Meira, Willian, et al.
Publicado: (2021)

The hen model of human ovarian cancer develops anti-mesothelin autoantibodies in response to mesothelin expressing tumors
por: Yu, Yi, et al.
Publicado: (2011)

Bone turnover markers are correlated with total skeletal uptake of (99m)Tc-methylene diphosphonate ((99m)Tc-MDP)
por: Lenora, Janaka, et al.
Publicado: (2009)

Comparison of Tc-99m pertechnetate images with dual-phase Tc 99m MIBI and SPECT images in primary hyperparathyroidism
por: Sager, Sait, et al.
Publicado: (2014)

Evaluation of interobserver variability of parenchymal phase of Tc-99m mercaptoacetyltriglycine and Tc-99m dimercaptosuccinic acid renal scintigraphy
por: Erdoğan, Zeynep, et al.
Publicado: (2014)

Comparison of [(99m)Tc]Tilmanocept and Filtered [(99m)Tc]Sulfur Colloid for Identification of SLNs in Breast Cancer Patients
por: Baker, Jennifer L., et al.
Publicado: (2014)

Comparison of the Relative Renal Function Calculated with 99mTc-Diethylenetriaminepentaacetic Acid and 99mTc-Dimercaptosuccinic Acid in Children
por: Çelik, Tanju, et al.
Publicado: (2014)

Comparison of Tc-99m maraciclatide and Tc-99m sestamibi molecular breast imaging in patients with suspected breast cancer
por: O’Connor, Michael K., et al.
Publicado: (2017)

Regional Liver Disorder with Differences in the Accumulation of (99m)Tc-phytate and (99m)Tc-galactosyl Human Serum Albumin
por: Kotani, Kohei, et al.
Publicado: (2017)

(99m)TcO(4)(-)/(99m)Tc-MIBI dual-tracer scintigraphy for preoperative localization of parathyroid adenomas
por: Huang, Zhongke, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_j2qm36rdd1dh7gbsa15cu388da