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Tyrosyl-DNA Phosphodiesterase 1 and Topoisomerase I Activities as Predictive Indicators for Glioblastoma Susceptibility to Genotoxic Agents

Glioblastoma (GBM) patients have an estimated survival of ~15 months with treatment, and the standard of care only modestly enhances patient survival. Identifying biomarkers representing vulnerabilities may allow for the selection of efficacious chemotherapy options to address personalized variation...

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Detalles Bibliográficos
Autores principales:	Wang, Wenjie, Rodriguez-Silva, Monica, Acanda de la Rocha, Arlet M., Wolf, Aizik L., Lai, Yanhao, Liu, Yuan, Reinhold, William C., Pommier, Yves, Chambers, Jeremy W., Tse-Dinh, Yuk-Ching
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827102/ https://www.ncbi.nlm.nih.gov/pubmed/31547492 http://dx.doi.org/10.3390/cancers11101416

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