Cargando…

Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism

Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a significant challenge due to the size and complexity of...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Lizong, Feng, Shuxin, Duan, Guiduo, Li, Ying, Liu, Guisong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827155/
https://www.ncbi.nlm.nih.gov/pubmed/31627420
http://dx.doi.org/10.3390/genes10100817
_version_ 1783465255430520832
author Zhang, Lizong
Feng, Shuxin
Duan, Guiduo
Li, Ying
Liu, Guisong
author_facet Zhang, Lizong
Feng, Shuxin
Duan, Guiduo
Li, Ying
Liu, Guisong
author_sort Zhang, Lizong
collection PubMed
description Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a significant challenge due to the size and complexity of retinal fundus images. Therefore, this paper presents a novel MA detection method based on a deep neural network with a multilayer attention mechanism for retinal fundus images. First, a series of equalization operations are performed to improve the quality of the fundus images. Then, based on the attention mechanism, multiple feature layers with obvious target features are fused to achieve preliminary MA detection. Finally, the spatial relationships between MAs and blood vessels are utilized to perform a secondary screening of the preliminary test results to obtain the final MA detection results. We evaluated the method on the IDRiD_VOC dataset, which was collected from the open IDRiD dataset. The results show that our method effectively improves the average accuracy and sensitivity of MA detection.
format Online
Article
Text
id pubmed-6827155
institution National Center for Biotechnology Information
language English
publishDate 2019
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-68271552019-11-18 Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism Zhang, Lizong Feng, Shuxin Duan, Guiduo Li, Ying Liu, Guisong Genes (Basel) Article Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a significant challenge due to the size and complexity of retinal fundus images. Therefore, this paper presents a novel MA detection method based on a deep neural network with a multilayer attention mechanism for retinal fundus images. First, a series of equalization operations are performed to improve the quality of the fundus images. Then, based on the attention mechanism, multiple feature layers with obvious target features are fused to achieve preliminary MA detection. Finally, the spatial relationships between MAs and blood vessels are utilized to perform a secondary screening of the preliminary test results to obtain the final MA detection results. We evaluated the method on the IDRiD_VOC dataset, which was collected from the open IDRiD dataset. The results show that our method effectively improves the average accuracy and sensitivity of MA detection. MDPI 2019-10-17 /pmc/articles/PMC6827155/ /pubmed/31627420 http://dx.doi.org/10.3390/genes10100817 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Zhang, Lizong
Feng, Shuxin
Duan, Guiduo
Li, Ying
Liu, Guisong
Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism
title Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism
title_full Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism
title_fullStr Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism
title_full_unstemmed Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism
title_short Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism
title_sort detection of microaneurysms in fundus images based on an attention mechanism
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827155/
https://www.ncbi.nlm.nih.gov/pubmed/31627420
http://dx.doi.org/10.3390/genes10100817
work_keys_str_mv AT zhanglizong detectionofmicroaneurysmsinfundusimagesbasedonanattentionmechanism
AT fengshuxin detectionofmicroaneurysmsinfundusimagesbasedonanattentionmechanism
AT duanguiduo detectionofmicroaneurysmsinfundusimagesbasedonanattentionmechanism
AT liying detectionofmicroaneurysmsinfundusimagesbasedonanattentionmechanism
AT liuguisong detectionofmicroaneurysmsinfundusimagesbasedonanattentionmechanism