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Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism
Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a significant challenge due to the size and complexity of...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827155/ https://www.ncbi.nlm.nih.gov/pubmed/31627420 http://dx.doi.org/10.3390/genes10100817 |
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author | Zhang, Lizong Feng, Shuxin Duan, Guiduo Li, Ying Liu, Guisong |
author_facet | Zhang, Lizong Feng, Shuxin Duan, Guiduo Li, Ying Liu, Guisong |
author_sort | Zhang, Lizong |
collection | PubMed |
description | Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a significant challenge due to the size and complexity of retinal fundus images. Therefore, this paper presents a novel MA detection method based on a deep neural network with a multilayer attention mechanism for retinal fundus images. First, a series of equalization operations are performed to improve the quality of the fundus images. Then, based on the attention mechanism, multiple feature layers with obvious target features are fused to achieve preliminary MA detection. Finally, the spatial relationships between MAs and blood vessels are utilized to perform a secondary screening of the preliminary test results to obtain the final MA detection results. We evaluated the method on the IDRiD_VOC dataset, which was collected from the open IDRiD dataset. The results show that our method effectively improves the average accuracy and sensitivity of MA detection. |
format | Online Article Text |
id | pubmed-6827155 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | MDPI |
record_format | MEDLINE/PubMed |
spelling | pubmed-68271552019-11-18 Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism Zhang, Lizong Feng, Shuxin Duan, Guiduo Li, Ying Liu, Guisong Genes (Basel) Article Microaneurysms (MAs) are the earliest detectable diabetic retinopathy (DR) lesions. Thus, the ability to automatically detect MAs is critical for the early diagnosis of DR. However, achieving the accurate and reliable detection of MAs remains a significant challenge due to the size and complexity of retinal fundus images. Therefore, this paper presents a novel MA detection method based on a deep neural network with a multilayer attention mechanism for retinal fundus images. First, a series of equalization operations are performed to improve the quality of the fundus images. Then, based on the attention mechanism, multiple feature layers with obvious target features are fused to achieve preliminary MA detection. Finally, the spatial relationships between MAs and blood vessels are utilized to perform a secondary screening of the preliminary test results to obtain the final MA detection results. We evaluated the method on the IDRiD_VOC dataset, which was collected from the open IDRiD dataset. The results show that our method effectively improves the average accuracy and sensitivity of MA detection. MDPI 2019-10-17 /pmc/articles/PMC6827155/ /pubmed/31627420 http://dx.doi.org/10.3390/genes10100817 Text en © 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
spellingShingle | Article Zhang, Lizong Feng, Shuxin Duan, Guiduo Li, Ying Liu, Guisong Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism |
title | Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism |
title_full | Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism |
title_fullStr | Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism |
title_full_unstemmed | Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism |
title_short | Detection of Microaneurysms in Fundus Images Based on an Attention Mechanism |
title_sort | detection of microaneurysms in fundus images based on an attention mechanism |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827155/ https://www.ncbi.nlm.nih.gov/pubmed/31627420 http://dx.doi.org/10.3390/genes10100817 |
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