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STING: a master regulator in the cancer-immunity cycle

The aberrant appearance of DNA in the cytoplasm triggers the activation of cGAS-cGAMP-STING signaling and induces the production of type I interferons, which play critical roles in activating both innate and adaptive immune responses. Recently, numerous studies have shown that the activation of STIN...

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Detalles Bibliográficos
Autores principales: Zhu, Yuanyuan, An, Xiang, Zhang, Xiao, Qiao, Yu, Zheng, Tongsen, Li, Xiaobo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827255/
https://www.ncbi.nlm.nih.gov/pubmed/31679519
http://dx.doi.org/10.1186/s12943-019-1087-y

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