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STING: a master regulator in the cancer-immunity cycle
The aberrant appearance of DNA in the cytoplasm triggers the activation of cGAS-cGAMP-STING signaling and induces the production of type I interferons, which play critical roles in activating both innate and adaptive immune responses. Recently, numerous studies have shown that the activation of STIN...
Autores principales: | Zhu, Yuanyuan, An, Xiang, Zhang, Xiao, Qiao, Yu, Zheng, Tongsen, Li, Xiaobo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827255/ https://www.ncbi.nlm.nih.gov/pubmed/31679519 http://dx.doi.org/10.1186/s12943-019-1087-y |
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