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A Na(+) leak channel cloned from Trichoplax adhaerens extends extracellular pH and Ca(2+) sensing for the DEG/ENaC family close to the base of Metazoa

Acid-sensitive ion channels belonging to the degenerin/epithelial sodium channel (DEG/ENaC) family activate in response to extracellular protons and are considered unique to deuterostomes. However, sensitivity to pH/protons is more widespread, where, for example, human ENaC Na(+) leak channels are p...

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Detalles Bibliográficos
Autores principales:	Elkhatib, Wassim, Smith, Carolyn L., Senatore, Adriano
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Biochemistry and Molecular Biology 2019
Materias:	Molecular Biophysics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827283/ https://www.ncbi.nlm.nih.gov/pubmed/31527080 http://dx.doi.org/10.1074/jbc.RA119.010542

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