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Germ Cell Lineage Homeostasis in Drosophila Requires the Vasa RNA Helicase

The conserved RNA helicase Vasa is required for germ cell development in many organisms. In Drosophila melanogaster loss of PIWI-interacting RNA pathway components, including Vasa, causes Chk2-dependent oogenesis arrest. However, whether the arrest is due to Chk2 signaling at a specific stage and wh...

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Detalles Bibliográficos
Autores principales: Durdevic, Zeljko, Ephrussi, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Genetics Society of America 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827371/
https://www.ncbi.nlm.nih.gov/pubmed/31484689
http://dx.doi.org/10.1534/genetics.119.302558

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