Primary Cutaneous Anaplastic Large-Cell Lymphoma

A 35-year-old male presented with a 6-month history of asymptomatic, generalised, self-healing lesions. On clinical examination, there were diffuse, ulcerated, necrotic papules and nodules with lymphoedema of the face. Histology sections confirmed atypical lymphoid-type cells which appeared round-to...

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Detalles Bibliográficos
Autores principales: Moodley, Nerissa, Nombona, Patiswa, Mosam, Anisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2019
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827451/
https://www.ncbi.nlm.nih.gov/pubmed/31700858
http://dx.doi.org/10.1159/000500259
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author Moodley, Nerissa
Nombona, Patiswa
Mosam, Anisa
author_facet Moodley, Nerissa
Nombona, Patiswa
Mosam, Anisa
author_sort Moodley, Nerissa
collection PubMed
description A 35-year-old male presented with a 6-month history of asymptomatic, generalised, self-healing lesions. On clinical examination, there were diffuse, ulcerated, necrotic papules and nodules with lymphoedema of the face. Histology sections confirmed atypical lymphoid-type cells which appeared round-to-oval with irregular nuclei (horseshoe-shaped). Immunohistochemistry stains were positive for CD30, CD3, and epithelial membrane antigen. The features were in keeping with an anaplastic large-cell lymphoma, T cell type. This transformed into a systemic variant of the disease after the patient had completed chemotherapy.
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spelling pubmed-68274512019-11-07 Primary Cutaneous Anaplastic Large-Cell Lymphoma Moodley, Nerissa Nombona, Patiswa Mosam, Anisa Dermatopathology (Basel) Case Report A 35-year-old male presented with a 6-month history of asymptomatic, generalised, self-healing lesions. On clinical examination, there were diffuse, ulcerated, necrotic papules and nodules with lymphoedema of the face. Histology sections confirmed atypical lymphoid-type cells which appeared round-to-oval with irregular nuclei (horseshoe-shaped). Immunohistochemistry stains were positive for CD30, CD3, and epithelial membrane antigen. The features were in keeping with an anaplastic large-cell lymphoma, T cell type. This transformed into a systemic variant of the disease after the patient had completed chemotherapy. S. Karger AG 2019-06-26 /pmc/articles/PMC6827451/ /pubmed/31700858 http://dx.doi.org/10.1159/000500259 Text en Copyright © 2019 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License (CC BY-NC-ND) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case Report
Moodley, Nerissa
Nombona, Patiswa
Mosam, Anisa
Primary Cutaneous Anaplastic Large-Cell Lymphoma
title Primary Cutaneous Anaplastic Large-Cell Lymphoma
title_full Primary Cutaneous Anaplastic Large-Cell Lymphoma
title_fullStr Primary Cutaneous Anaplastic Large-Cell Lymphoma
title_full_unstemmed Primary Cutaneous Anaplastic Large-Cell Lymphoma
title_short Primary Cutaneous Anaplastic Large-Cell Lymphoma
title_sort primary cutaneous anaplastic large-cell lymphoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827451/
https://www.ncbi.nlm.nih.gov/pubmed/31700858
http://dx.doi.org/10.1159/000500259
work_keys_str_mv AT moodleynerissa primarycutaneousanaplasticlargecelllymphoma
AT nombonapatiswa primarycutaneousanaplasticlargecelllymphoma
AT mosamanisa primarycutaneousanaplasticlargecelllymphoma

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