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A High-Resolution View of Adaptive Event Dynamics in a Plasmid

Coadaptation between bacterial hosts and plasmids frequently results in adaptive changes restricted exclusively to host genome leaving plasmids unchanged. To better understand this remarkable stability, we transformed naïve Escherichia coli cells with a plasmid carrying an antibiotic-resistance gene...

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Detalles Bibliográficos
Autores principales: Mei, Han, Arbeithuber, Barbara, Cremona, Marzia A, DeGiorgio, Michael, Nekrutenko, Anton
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827461/
https://www.ncbi.nlm.nih.gov/pubmed/31539047
http://dx.doi.org/10.1093/gbe/evz197