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Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction
BACKGROUND: Sleep disorders (SDs) are usually associated with an increase in frequency of ventricular tachycardia (VT). However, the relationship between SDs and the prevalence of VT within the first week of acute myocardial infarction (AMI) remains unclear. This study aimed to evaluate their associ...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827508/ https://www.ncbi.nlm.nih.gov/pubmed/31802960 http://dx.doi.org/10.2147/NSS.S222359 |
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author | Wang, Shipeng Gao, Hui Ru, Zewen Zou, Yanan Li, Yilan Cao, Wei Meng, Wei Li, Jihe Yao, Yuan Zhang, Yanxiu Lang, Xueyan Zhang, Yao |
author_facet | Wang, Shipeng Gao, Hui Ru, Zewen Zou, Yanan Li, Yilan Cao, Wei Meng, Wei Li, Jihe Yao, Yuan Zhang, Yanxiu Lang, Xueyan Zhang, Yao |
author_sort | Wang, Shipeng |
collection | PubMed |
description | BACKGROUND: Sleep disorders (SDs) are usually associated with an increase in frequency of ventricular tachycardia (VT). However, the relationship between SDs and the prevalence of VT within the first week of acute myocardial infarction (AMI) remains unclear. This study aimed to evaluate their associations and potential mechanisms. METHODS: This structured questionnaire-based cross-sectional study enrolled 303 patients with AMI from a hospital in northern China. Pittsburgh Sleep Quality Index (PSQI) was used to determine sleep quality of subjects. Heart rate variability (HRV) of patients was investigated by ambulatory electrocardiography recorders. Enzyme-linked immunosorbent assay was used to measure the plasma levels of catecholamine in a subgroup including 80 patients with AMI. RESULTS: After adjusting to basic cardiovascular characteristics, results of multivariate logistic regression demonstrated that the global PSQI score and its main components were positively associated with VT prevalence in inpatients with AMI. There were significantly different HRV parameters interpreted as autonomic nerve activity in two groups of AMI patients with different sleep quality. In addition, we found the influence of sleep quality on plasma concentrations of adrenaline and norepinephrine in AMI patients. CONCLUSION: Sleep status was significantly associated with the initiation of VT within the first week of AMI, probably due to the effect of SDs on sympathetic nerve activity. Amelioration of sleep quality and sympathetic hyperactivity may be prospective strategy to curb arrhythmias after AMI. |
format | Online Article Text |
id | pubmed-6827508 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2019 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-68275082019-12-04 Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction Wang, Shipeng Gao, Hui Ru, Zewen Zou, Yanan Li, Yilan Cao, Wei Meng, Wei Li, Jihe Yao, Yuan Zhang, Yanxiu Lang, Xueyan Zhang, Yao Nat Sci Sleep Original Research BACKGROUND: Sleep disorders (SDs) are usually associated with an increase in frequency of ventricular tachycardia (VT). However, the relationship between SDs and the prevalence of VT within the first week of acute myocardial infarction (AMI) remains unclear. This study aimed to evaluate their associations and potential mechanisms. METHODS: This structured questionnaire-based cross-sectional study enrolled 303 patients with AMI from a hospital in northern China. Pittsburgh Sleep Quality Index (PSQI) was used to determine sleep quality of subjects. Heart rate variability (HRV) of patients was investigated by ambulatory electrocardiography recorders. Enzyme-linked immunosorbent assay was used to measure the plasma levels of catecholamine in a subgroup including 80 patients with AMI. RESULTS: After adjusting to basic cardiovascular characteristics, results of multivariate logistic regression demonstrated that the global PSQI score and its main components were positively associated with VT prevalence in inpatients with AMI. There were significantly different HRV parameters interpreted as autonomic nerve activity in two groups of AMI patients with different sleep quality. In addition, we found the influence of sleep quality on plasma concentrations of adrenaline and norepinephrine in AMI patients. CONCLUSION: Sleep status was significantly associated with the initiation of VT within the first week of AMI, probably due to the effect of SDs on sympathetic nerve activity. Amelioration of sleep quality and sympathetic hyperactivity may be prospective strategy to curb arrhythmias after AMI. Dove 2019-10-31 /pmc/articles/PMC6827508/ /pubmed/31802960 http://dx.doi.org/10.2147/NSS.S222359 Text en © 2019 Wang et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Wang, Shipeng Gao, Hui Ru, Zewen Zou, Yanan Li, Yilan Cao, Wei Meng, Wei Li, Jihe Yao, Yuan Zhang, Yanxiu Lang, Xueyan Zhang, Yao Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction |
title | Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction |
title_full | Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction |
title_fullStr | Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction |
title_full_unstemmed | Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction |
title_short | Poor Sleep Quality Associated With High Risk Of Ventricular Tachycardia After Acute Myocardial Infarction |
title_sort | poor sleep quality associated with high risk of ventricular tachycardia after acute myocardial infarction |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827508/ https://www.ncbi.nlm.nih.gov/pubmed/31802960 http://dx.doi.org/10.2147/NSS.S222359 |
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