Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition

Cardiac fibrosis is a common feature in chronic hypertension patients with advanced heart failure, and endothelial-to-mesenchymal transition (EndMT) is known to promote Angiotensin II (Ang II)-mediated cardiac fibrosis. Previous studies have suggested a potential role for the transcription factor, E...

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Autores principales: Xu, Lian, Fu, Mengxia, Chen, Dongrui, Han, Weiqing, Ostrowski, Michael C., Grossfeld, Paul, Gao, Pingjin, Ye, Maoqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Korean Society for Biochemistry and Molecular Biology 2019
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827575/
https://www.ncbi.nlm.nih.gov/pubmed/30670148
http://dx.doi.org/10.5483/BMBRep.2019.52.10.206

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