Cargando…
Mutations of the Bacillus subtilis YidC1 (SpoIIIJ) insertase alleviate stress associated with σ(M)-dependent membrane protein overproduction
In Bacillus subtilis, the extracytoplasmic function σ factor σ(M) regulates cell wall synthesis and is critical for intrinsic resistance to cell wall targeting antibiotics. The anti-σ factors YhdL and YhdK form a complex that restricts the basal activity of σ(M), and the absence of YhdL leads to run...
| Autores principales: | , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2019
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827917/ https://www.ncbi.nlm.nih.gov/pubmed/31626625 http://dx.doi.org/10.1371/journal.pgen.1008263 |