Integrated pan-cancer gene expression and drug sensitivity analysis reveals SLFN11 mRNA as a solid tumor biomarker predictive of sensitivity to DNA-damaging chemotherapy

BACKGROUND: Precision oncology seeks to integrate multiple layers of data from a patient’s cancer to effectively tailor therapy. Conventional chemotherapies are sometimes effective but accompanied by adverse events, warranting the identification of a biomarker of chemosensitivity. OBJECTIVE: Identif...

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Detalles Bibliográficos
Autores principales: Shee, Kevin, Wells, Jason D., Jiang, Amanda, Miller, Todd W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2019
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827986/
https://www.ncbi.nlm.nih.gov/pubmed/31682620
http://dx.doi.org/10.1371/journal.pone.0224267

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6827986/
https://www.ncbi.nlm.nih.gov/pubmed/31682620
http://dx.doi.org/10.1371/journal.pone.0224267

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