Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury

Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of th...

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Autores principales: Kang, Xianhui, Zuo, Ziyi, Hong, Wandong, Tang, Hongli, Geng, Wujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828609/
https://www.ncbi.nlm.nih.gov/pubmed/31736691
http://dx.doi.org/10.3389/fnins.2019.01149
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author Kang, Xianhui
Zuo, Ziyi
Hong, Wandong
Tang, Hongli
Geng, Wujun
author_facet Kang, Xianhui
Zuo, Ziyi
Hong, Wandong
Tang, Hongli
Geng, Wujun
author_sort Kang, Xianhui
collection PubMed
description Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of their high biocompatibility and low immunogenicity and toxicity, exosomes have attracted increasing attention as an attractive drug delivery system. This article reviews the relevant studies that have shown that exosomes play an important role in protective mechanisms against ischemic brain injury.
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spelling pubmed-68286092019-11-15 Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury Kang, Xianhui Zuo, Ziyi Hong, Wandong Tang, Hongli Geng, Wujun Front Neurosci Neuroscience Exosomes, as a type of extracellular vesicle (EV), are lipid bilayer vesicles 20–100 nm in diameter that can cross the blood-brain barrier. Exosomes are important transport vesicles in the human body that participate in many conduction pathways and play an important physiological role. Because of their high biocompatibility and low immunogenicity and toxicity, exosomes have attracted increasing attention as an attractive drug delivery system. This article reviews the relevant studies that have shown that exosomes play an important role in protective mechanisms against ischemic brain injury. Frontiers Media S.A. 2019-10-29 /pmc/articles/PMC6828609/ /pubmed/31736691 http://dx.doi.org/10.3389/fnins.2019.01149 Text en Copyright © 2019 Kang, Zuo, Hong, Tang and Geng. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Kang, Xianhui
Zuo, Ziyi
Hong, Wandong
Tang, Hongli
Geng, Wujun
Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_full Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_fullStr Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_full_unstemmed Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_short Progress of Research on Exosomes in the Protection Against Ischemic Brain Injury
title_sort progress of research on exosomes in the protection against ischemic brain injury
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828609/
https://www.ncbi.nlm.nih.gov/pubmed/31736691
http://dx.doi.org/10.3389/fnins.2019.01149
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