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Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease

Cardiovascular disease (CVD) remains the leading cause of death in chronic kidney disease (CKD) patients despite treatment of traditional risk factors, suggesting that non-traditional CVD risk factors are involved. Trimethylamine-N-oxide (TMAO) correlates with atherosclerosis burden in CKD patients...

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Detalles Bibliográficos
Autores principales: Prokopienko, Alexander J., West, Raymond E., Schrum, Daniel P., Stubbs, Jason R., Leblond, François A., Pichette, Vincent, Nolin, Thomas D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828678/
https://www.ncbi.nlm.nih.gov/pubmed/31685846
http://dx.doi.org/10.1038/s41598-019-52032-9

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