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Metabolic Activation of Flavin Monooxygenase-mediated Trimethylamine-N-Oxide Formation in Experimental Kidney Disease
Cardiovascular disease (CVD) remains the leading cause of death in chronic kidney disease (CKD) patients despite treatment of traditional risk factors, suggesting that non-traditional CVD risk factors are involved. Trimethylamine-N-oxide (TMAO) correlates with atherosclerosis burden in CKD patients...
Autores principales: | Prokopienko, Alexander J., West, Raymond E., Schrum, Daniel P., Stubbs, Jason R., Leblond, François A., Pichette, Vincent, Nolin, Thomas D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828678/ https://www.ncbi.nlm.nih.gov/pubmed/31685846 http://dx.doi.org/10.1038/s41598-019-52032-9 |
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