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A protective role for N-acylphosphatidylethanolamine phospholipase D in 6-OHDA-induced neurodegeneration
N-acylphosphatidylethanolamine phospholipase D (NAPE-PLD) catalyzes the cleavage of membrane NAPEs into bioactive fatty-acid ethanolamides (FAEs). Along with this precursor role, NAPEs might also serve autonomous signaling functions. Here, we report that injections of 6-hydroxydopamine (6-OHDA) into...
Autores principales: | Palese, Francesca, Pontis, Silvia, Realini, Natalia, Piomelli, Daniele |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828692/ https://www.ncbi.nlm.nih.gov/pubmed/31685899 http://dx.doi.org/10.1038/s41598-019-51799-1 |
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