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The p75 Neurotrophin Receptor Facilitates TrkB Signaling and Function in Rat Hippocampal Neurons

Neurotrophins activate Trk receptor signaling to support neuronal survival and many aspects of neuronal function. Early studies demonstrated that TrkA formed a complex with the p75 neurotrophin receptor (p75(NTR)), which increased the affinity and selectivity of NGF binding, however, whether interac...

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Detalles Bibliográficos
Autores principales: Zanin, Juan P., Montroull, Laura E., Volosin, Marta, Friedman, Wilma J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828739/
https://www.ncbi.nlm.nih.gov/pubmed/31736712
http://dx.doi.org/10.3389/fncel.2019.00485