Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes

Ischaemic heart disease (IHD) is the leading cause of death worldwide. Although myocardial cell death plays a significant role in myocardial infarction (MI), its underlying mechanism remains to be elucidated. To understand the progression of MI and identify potential therapeutic targets, we performe...

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Detalles Bibliográficos
Autores principales: Park, Tae-Jun, Park, Jei Hyoung, Lee, Ga Seul, Lee, Ji-Yoon, Shin, Ji Hye, Kim, Min Wook, Kim, Yong Sook, Kim, Jeong-Yoon, Oh, Kyoung-Jin, Han, Baek-Soo, Kim, Won-Kon, Ahn, Youngkeun, Moon, Jeong Hee, Song, Jaewhan, Bae, Kwang-Hee, Kim, Do Han, Lee, Eun-Woo, Lee, Sang Chul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828761/
https://www.ncbi.nlm.nih.gov/pubmed/31685805
http://dx.doi.org/10.1038/s41419-019-2061-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828761/
https://www.ncbi.nlm.nih.gov/pubmed/31685805
http://dx.doi.org/10.1038/s41419-019-2061-8

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