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Quantitative proteomic analyses reveal that GPX4 downregulation during myocardial infarction contributes to ferroptosis in cardiomyocytes
Ischaemic heart disease (IHD) is the leading cause of death worldwide. Although myocardial cell death plays a significant role in myocardial infarction (MI), its underlying mechanism remains to be elucidated. To understand the progression of MI and identify potential therapeutic targets, we performe...
Autores principales: | Park, Tae-Jun, Park, Jei Hyoung, Lee, Ga Seul, Lee, Ji-Yoon, Shin, Ji Hye, Kim, Min Wook, Kim, Yong Sook, Kim, Jeong-Yoon, Oh, Kyoung-Jin, Han, Baek-Soo, Kim, Won-Kon, Ahn, Youngkeun, Moon, Jeong Hee, Song, Jaewhan, Bae, Kwang-Hee, Kim, Do Han, Lee, Eun-Woo, Lee, Sang Chul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828761/ https://www.ncbi.nlm.nih.gov/pubmed/31685805 http://dx.doi.org/10.1038/s41419-019-2061-8 |
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