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Localized delivery of compounds into articular cartilage by using high-intensity focused ultrasound
Localized delivery of drugs into an osteoarthritic cartilaginous lesion does not yet exist, which limits pharmaceutical management of osteoarthritis (OA). High-intensity focused ultrasound (HIFU) provides a means to actuate matter from a distance in a non-destructive way. In this study, we aimed to...
Autores principales: | Nieminen, Heikki J., Lampsijärvi, Eetu, Barreto, Gonçalo, Finnilä, Mikko A. J., Salmi, Ari, Airaksinen, Anu J., Eklund, Kari K., Saarakkala, Simo, Pritzker, Kenneth P. H., Hæggström, Edward |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828772/ https://www.ncbi.nlm.nih.gov/pubmed/31685841 http://dx.doi.org/10.1038/s41598-019-52012-z |
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