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Pancreatic cancer-educated macrophages protect cancer cells from complement-dependent cytotoxicity by up-regulation of CD59

Tumor-associated macrophages (TAMs) are versatile immune cells that promote a variety of malignant behaviors of pancreatic cancer. CD59 is a GPI-anchored membrane protein that prevents complement activation by inhibiting the formation of the membrane attack complex, which may protect cancer cells fr...

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Detalles Bibliográficos
Autores principales:	Zhang, Ronghua, Liu, Qiaofei, Peng, Junya, Wang, Mengyi, Gao, Xiang, Liao, Quan, Zhao, Yupei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2019
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828776/ https://www.ncbi.nlm.nih.gov/pubmed/31685825 http://dx.doi.org/10.1038/s41419-019-2065-4

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