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Mincle and STING-Stimulating Adjuvants Elicit Robust Cellular Immunity and Drive Long-Lasting Memory Responses in a Foot-and-Mouth Disease Vaccine

Conventional foot-and-mouth disease (FMD) vaccines exhibit several limitations, such as the slow induction of antibodies, short-term persistence of antibody titers, as well as low vaccine efficacy and safety, in pigs. Despite the importance of cellular immune response in host defense at the early st...

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Detalles Bibliográficos
Autores principales: Lee, Min Ja, Jo, Hyundong, Shin, Sung Ho, Kim, Su-Mi, Kim, Byounghan, Shim, Hang Sub, Park, Jong-Hyeon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828931/
https://www.ncbi.nlm.nih.gov/pubmed/31736952
http://dx.doi.org/10.3389/fimmu.2019.02509