Recombinant Thrombomodulin Suppresses Histone-Induced Neutrophil Extracellular Trap Formation

Histones, the major protein components of chromatin, are released into the extracellular space during sepsis, trauma, and ischemia-reperfusion injury, and subsequently mediate organ failure. Extracellular histones can promote endothelial damage and platelet aggregation, which can be suppressed by ad...

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Detalles Bibliográficos
Autores principales: Shrestha, Binita, Ito, Takashi, Kakuuchi, Midori, Totoki, Takaaki, Nagasato, Tomoka, Yamamoto, Mika, Maruyama, Ikuro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828967/
https://www.ncbi.nlm.nih.gov/pubmed/31736962
http://dx.doi.org/10.3389/fimmu.2019.02535

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828967/
https://www.ncbi.nlm.nih.gov/pubmed/31736962
http://dx.doi.org/10.3389/fimmu.2019.02535

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