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Recombinant Thrombomodulin Suppresses Histone-Induced Neutrophil Extracellular Trap Formation
Histones, the major protein components of chromatin, are released into the extracellular space during sepsis, trauma, and ischemia-reperfusion injury, and subsequently mediate organ failure. Extracellular histones can promote endothelial damage and platelet aggregation, which can be suppressed by ad...
| Autores principales: | , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828967/ https://www.ncbi.nlm.nih.gov/pubmed/31736962 http://dx.doi.org/10.3389/fimmu.2019.02535 |