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The Role of Tumor Microenvironment in Genomic Instability of Malignant Tumors
Genomic instability is an essential feature of cancer cells. The somatic mutation theory suggests that along with inherited ones, the changes in DNA caused by environmental factors may cause cancer. Although approximately 50–60 mutations per tumor are observed in established cancer tissue, it is kno...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2019
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828977/ https://www.ncbi.nlm.nih.gov/pubmed/31737046 http://dx.doi.org/10.3389/fgene.2019.01063 |