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The Role of Tumor Microenvironment in Genomic Instability of Malignant Tumors

Genomic instability is an essential feature of cancer cells. The somatic mutation theory suggests that along with inherited ones, the changes in DNA caused by environmental factors may cause cancer. Although approximately 50–60 mutations per tumor are observed in established cancer tissue, it is kno...

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Detalles Bibliográficos
Autores principales: Sonugür, F. Gizem, Akbulut, Hakan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828977/
https://www.ncbi.nlm.nih.gov/pubmed/31737046
http://dx.doi.org/10.3389/fgene.2019.01063