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Rapid and Definitive Analysis of In Vitro DNA Methylation by Nano-electrospray Ionization Mass Spectrometry

CpG methylation of DNA is an epigenetic marker that is highly related to the regulation of transcription initiation. For analysis of CpG methylation in genomic DNA sequences, bisulfite-induced modification in combination with polymerase chain reaction (PCR) is usually utilized, but it cannot be stra...

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Detalles Bibliográficos
Autores principales: Ushijima, Hiroshi, Maekawa, Rena, Igarashi, Eri, Akashi, Satoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6828984/
https://www.ncbi.nlm.nih.gov/pubmed/31529403
http://dx.doi.org/10.1007/s13361-019-02304-5