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Rationale and Design for a Phase 1 Study of N-Acetylmannosamine for Primary Glomerular Diseases

INTRODUCTION: Sialic acids are important contributors to the polyanionic component of the glomerular filtration barrier, which regulates permeability selectivity. Pathologic glomerular hyposialylation, associated with podocyte effacement, has been implicated in human and mouse glomerulopathies. Oral...

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Detalles Bibliográficos
Autores principales:	Huizing, Marjan, Yardeni, Tal, Fuentes, Federico, Malicdan, May C.V., Leoyklang, Petcharat, Volkov, Alexander, Dekel, Benjamin, Brede, Emily, Blake, Jodi, Powell, Alva, Chatrathi, Harish, Anikster, Yair, Carrillo, Nuria, Gahl, William A., Kopp, Jeffrey B.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2019
Materias:	Translational Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829193/ https://www.ncbi.nlm.nih.gov/pubmed/31701055 http://dx.doi.org/10.1016/j.ekir.2019.06.012

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