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Glomerular Complement Factor H–Related Protein 5 (FHR5) Is Highly Prevalent in C3 Glomerulopathy and Associated With Renal Impairment
INTRODUCTION: Therapeutic agents that target complement are increasingly available for glomerular diseases. However, the mechanisms linking glomerular complement deposition with inflammation and damage are incompletely understood. Complement factor H–related protein 5 (FHR5) interacts with complemen...
Autores principales: | Medjeral-Thomas, Nicholas R., Moffitt, Hilary, Lomax-Browne, Hannah J., Constantinou, Nicholas, Cairns, Tom, Cook, H. Terence, Pickering, Matthew C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829196/ https://www.ncbi.nlm.nih.gov/pubmed/31701048 http://dx.doi.org/10.1016/j.ekir.2019.06.008 |
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