Co-Stimulation of Purinergic P2X4 and Prostanoid EP3 Receptors Triggers Synergistic Degranulation in Murine Mast Cells

Mast cells (MCs) recognize antigens (Ag) via IgE-bound high affinity IgE receptors (FcεRI) and trigger type I allergic reactions. FcεRI-mediated MC activation is regulated by various G protein-coupled receptor (GPCR) agonists. We recently reported that ionotropic P2X4 receptor (P2X4R) stimulation en...

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Detalles Bibliográficos
Autores principales: Yoshida, Kazuki, Tajima, Makoto, Nagano, Tomoki, Obayashi, Kosuke, Ito, Masaaki, Yamamoto, Kimiko, Matsuoka, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829402/
https://www.ncbi.nlm.nih.gov/pubmed/31627451
http://dx.doi.org/10.3390/ijms20205157

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829402/
https://www.ncbi.nlm.nih.gov/pubmed/31627451
http://dx.doi.org/10.3390/ijms20205157

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