Leptin Promotes Expression of EMT-Related Transcription Factors and Invasion in a Src and FAK-Dependent Pathway in MCF10A Mammary Epithelial Cells

Leptin is one of the main adipokines secreted in breast tissue. Leptin promotes epithelial–mesenchymal transition (EMT), cell migration and invasion in epithelial breast cells, leading to tumor progression. Although, the molecular mechanisms that underlie these events are not fully understood, the a...

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Detalles Bibliográficos
Autores principales: Olea-Flores, Monserrat, Zuñiga-Eulogio, Miriam, Tacuba-Saavedra, Arvey, Bueno-Salgado, Magdalena, Sánchez-Carvajal, Andrea, Vargas-Santiago, Yovani, Mendoza-Catalán, Miguel A., Pérez Salazar, Eduardo, García-Hernández, Alejandra, Padilla-Benavides, Teresita, Navarro-Tito, Napoleón
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829404/
https://www.ncbi.nlm.nih.gov/pubmed/31554180
http://dx.doi.org/10.3390/cells8101133

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