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Upregulation of Lysyl Oxidase Expression in Vitreous of Diabetic Subjects: Implications for Diabetic Retinopathy

Animal studies have shown diabetes-induced lysyl oxidase (LOX) upregulation promotes blood-retinal-barrier breakdown and retinal vascular cell loss associated with diabetic retinopathy (DR). However, it is unclear whether changes in LOX expression contribute to the development and progression of DR....

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Detalles Bibliográficos
Autores principales: Subramanian, Manju L., Stein, Thor D., Siegel, Nicole, Ness, Steven, Fiorello, Marissa G., Kim, Dongjoon, Roy, Sayon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829411/
https://www.ncbi.nlm.nih.gov/pubmed/31546618
http://dx.doi.org/10.3390/cells8101122