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New Phosphorus Analogs of Bevirimat: Synthesis, Evaluation of Anti-HIV-1 Activity and Molecular Docking Study

Since the beginning of the human immunodeficiency virus (HIV) epidemic, many groups of drugs characterized by diverse mechanisms of action have been developed, which can suppress HIV viremia. 3-O-(3′,3′-Dimethylsuccinyl) betulinic acid, known as bevirimat (BVM), was the first compound in the class o...

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Detalles Bibliográficos
Autores principales: Chrobak, Elwira, Marciniec, Krzysztof, Dąbrowska, Aleksandra, Pęcak, Paweł, Bębenek, Ewa, Kadela-Tomanek, Monika, Bak, Andrzej, Jastrzębska, Maria, Boryczka, Stanisław
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6829466/
https://www.ncbi.nlm.nih.gov/pubmed/31640137
http://dx.doi.org/10.3390/ijms20205209